Dietbacs®

30 capsules per pack, intake for 30 days

Only the probiotic bacterial strains that have been studied in the most studies and have shown the best efficacy are included in our synbiotics.

5 bacterial strains - 50 billion colony forming units (CFUs):

• Lactobacillus acidophilus CUL60
• Lactobacillus acidophilus CUL21
• Lactobacillus plantarum CUL66
• Bifidobacterium animalis subsp. Lactis CUL34
• Bifidobacterium bifidum CUL20

Other ingredients:

• Reducose® 5% mulberry leaf extract
• 25% inulin from chicory root
• Hydroxypropylmethylcellulose (vegetarian capsule shell)
• Maltodextrin
• Microcrystalline cellulose
• Magnesium salts of fatty acids
• Colorant calcium carbonate (capsule shell)

The intake takes place daily.

Ideally, take one capsule with a glass of water 30 minutes before the largest meal or stir the capsule contents into water or yogurt if you have difficulty swallowing.

• White mulberry leaf extract/Reducose® can help maintain the balance of carbohydrate metabolism in the body.

Bacterial strains

Michael, DR, Jack, AA, Masetti, G., Davies, TS, Loxley, KE, Kerry-Smith, J., Plummer, JF, Marchesi, JR, Mullish, BH, McDonald, JAK, Hughes, TR, Wang, D., Garaiova, I., Paduchová, Z., Muchová, J., Good, MA, & Plummer, SF (2020). A randomized controlled study shows supplementation of overweight and obese adults with lactobacilli and bifidobacteria reduces body weight and improves well-being. Scientific reports, 10(1), 4183.

Michael, DR, Davies, TS, Jack, AA, Masetti, G., Marchesi, JR, Wang, D., ... & Plummer, SF (2021). Daily supplementation with the Lab4P probiotic consortium induces significant weight loss in overweight adults. Scientific reports, 11(1), 5.

Reducose® / Mulberry leaf extract

Cui W, Luo K, Xiao Q, et al. (2023). Effect of mulberry leaf or mulberry leaf extract on glycemic traits: a systematic review and meta-analysis.

Mohamed M, Zagury RL, Bhaskaran K, et al. (2023): A Randomized, Placebo-Controlled Crossover Study to Evaluate Postprandial Glucometabolic Effects of Mulberry Leaf Extract, Vitamin D, Chromium, and Fiber in People with Type 2 Diabetes. Diabetes Ther. doi: 10.1007/s13300-023-01379-4.

Ding F, Wang Q, Xie C, et al. (2023): The impact of mulberry leaf extract at three different levels on reducing the glycemic index of white bread. PLoS One

Wang R, Li Y, Mu W, et al. (2018): Mulberry leaf extract reduces the glycemic indexes of four common dietary carbohydrates. Medicine (Baltimore).

Reducose® turns fast sugars and carbs into slow ones

Bae U, Jung E, Jung S, et al. (2018). Mulberry leaf extract displays antidiabetic activity in db/db mice via Akt and AMP-activated protein kinase phosphorylation. Food Nutr Res.

Chau C., Wu S. (2006): The development of regulations of Chinese herbal medicines for both medicinal and food uses. Trends in Food Science & Technology

Lown M, Fuller R, Lightowler H, et al. (2017). Mulberry-extract improves glucose tolerance and decreases insulin concentrations in normoglycaemic adults: Results of a randomized double-blind placebo-controlled study. PLoS One.

Liu Y, Li X, Xie C, et al. (2016). Prevention Effects and Possible Molecular Mechanism of Mulberry Leaf Extract and its Formulation on Rats with Insulin Insensitivity. PLoS One

Nash R, Kato A, Fleet GW (2011). Iminosugars as therapeutic agents: recent advances and promising trends. Future Med Chem.

Song W, Wang H, Bucheli P, et al. (2009). Phytochemical profiles of different mulberry (Morus sp.) species from China. J Agric Food Chem.

Srivastava S, Kapoor R, Thathola A, et al. (2006). Nutritional quality of leaves of some genotypes of mulberry (Morus alba). Int J Food Sci Nutr

Thondre PS, Lightowler H, Ahlstrom L, et al. (2021). Mulberry leaf extract improves glycaemic response and insulaemic response to sucrose in healthy subjects: results of a randomized, double blind, placebo-controlled study. Nutr Metab (Lond.

Kim J, Yun E, Quan F, et al. (2017).Central Administration of 1-Deoxynojirimycin Attenuates Hypothalamic Endoplasmic Reticulum Stress and Regulates Food Intake and Body Weight in Mice with High-Fat Diet-Induced Obesity. Evid Based Complement Alternate Med.

Glycaemic index / glucose / second meal effect

Gheldof N, Francey C, Rytz A, et al. (2022). Effect of Different Nutritional Supplements on Glucose Response of Complete Meals in Two Crossover Studies. Nutrients.

Campbell GJ, Senior AM, Bell-Anderson KS et al. (2017): Metabolic Effects of High Glycemic Index Diets: A Systematic Review and Meta-Analysis of Feeding Studies in Mice and Rats. Nutrients.

Thomas DE, Elliott EJ et al. (2010). The use of low-glycaemic index diets in diabetes control. Br J Nutr..

Fletcher JA, Perfield II JW, Thyfault JP et al. (2012). The Second Meal Effect and Its Influence on Glycemia. J Nutr Disorders Ther.

Goff LM, Cowland DE, Hooper L, et al. (2013). Low glycaemic index diets and blood lipids: a systematic review and meta-analysis of randomized controlled trials. Nutr Metab Cardiovasc Dis.

Henry CJ, Kaur B, Quek R, et al. (2017). A Low Glycaemic Index Diet Incorporating Isomaltulose Is Associated with Lower Glycaemic Response and Variability, and Promotes Fat Oxidation in Asians.

Holmes R (1971). Carbohydrate digestion and absorption. J Clin Pathol Suppl (R Coll Pathol). 5:10–13.

Ojo O, Ojo OO, Adebowale F, et al. (2018). The Effect of Dietary Glycaemic Index on Glycaemia in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Nutrients.

Philippou E, Constantinou M (2014). The influence of glycemic index on cognitive functioning: a systematic review of the evidence. Adv Nutr.

Miller RA, Harrison DE, Allison DB, et al. (2020). Canagliflozin extends life span in genetically heterogeneous male but not female mice. JCI Insight.

Fiber and prebiotics

Slavin J (2013). Fiber and Prebiotics: Mechanisms and Health Benefits. Nutrients

Acarbose

Strong R, Miller RA, Antebi A, et al. (2016). Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α-glucosidase inhibitor or a Nrf2 inducer. Aging cells.