Dailybacs® Women

30 capsules per pack, intake for 30 days

Only the probiotic bacterial strains that have been studied in the most studies and have shown the best efficacy are included in our synbiotics.

11 bacterial strains - 60 billion colony forming units (CFUs):

• Bifidobacterium breve BR03
• Lactobacillus plantarum LP01
• Bifidobacterium longum BL03
• Bifidobacterium animalis subsp. lactis BS01
• Lactobacillus rhamnosus LR06
• Bifidobacterium infantis BI02
• Lactobacillus crispatus LCR01
• Lactobacillus salivarius subsp. salivarius CRL 1328
• Lactobacillus rhamnosus GG
• Bifidobacterium longum BB536
• Bifidobacterium breve M-16V

Other ingredients:

• Inulin
• Vitamin C 12mg
• Zinc 1.5mg
• Iron 2.1mg
• Vitamin D 0.75µg
• Folic acid 30µg
• D-Biotin 7.5µg
• Anti-caking agent: magnesium salts of fatty acids
• Modified corn starch
• Calcium carbonate (capsule shell)
• Hydroxypropylmethylcellulose (vegetarian capsule shell)

The intake takes place daily, ideally on an empty stomach in the morning.

One capsule approximately 30 minutes before breakfast Take with a glass of water or stir the capsule contents into water or yogurt if you have difficulty swallowing.

• Vitamin C and zinc contribute to the normal function of the immune system (Regulation (EU) No. 432/2012).
• Vitamin C contributes to normal energy metabolism (Regulation (EU) No. 432/2012).
• Vitamin D contributes to the normal absorption and utilization of calcium and phosphorus (Regulation (EU) No. 432/2012)

Gastrointestinal

Saggioro, A. (2004). Probiotics in the treatment of irritable bowel syndrome. Journal of clinical gastroenterology, 38, S104-S106.

Martínez-Martínez, MI, et al. (2017). The effect of probiotics as a treatment for constipation in elderly people: A systematic review. Archives of gerontology and geriatrics, 71, 142-149

Del Piano, M., et al. (2010). The use of probiotics in healthy volunteers with evacuation disorders and hard stools: a double-blind, randomized, placebo-controlled study. Journal of clinical gastroenterology, 44, S30-S34

Klemenak, M., et al. (2015). Administration of Bifidobacterium breve Decreases the Production of TNF-α in Children with Celiac Disease. Digestive diseases and sciences, 60(11), 3386-3392.

Del Piano, M., et al. (2008). In vitro sensitivity of probiotics to human pancreatic juice. Journal of clinical gastroenterology, 42, S170-S173.

Mogna, L., et al. (2012). Assessment of the in vitro inhibitory activity of specific probiotic bacteria against different Escherichia coli strains. Journal of clinical gastroenterology, 46, S29-S32.

Del Piano, M., et al. (2014). Correlation between chronic treatment with proton pump inhibitors and bacterial overgrowth in the stomach: any possible beneficial role for selected lactobacilli?. Journal of clinical gastroenterology, 48, S40-S46.

Dimidi, E., et al. (2014). The effect of probiotics on functional constipation in adults: a systematic review and meta-analysis of randomized controlled trials. The American journal of clinical nutrition, 100(4), 1075-1084.

Ogata, T., et al. (1997). Effect of Bifidobacterium longum BB536 administration on the intestinal environment, defecation frequency and fecal characteristics of human volunteers. Bioscience and Microflora, 16(2), 53-58.

Odamaki, T., et al. (2012). Effect of the oral intake of yogurt containing Bifidobacterium longum BB536 on the cell numbers of enterotoxigenic Bacteroides fragilis in microbiota. Anaerobic, 18(1), 14-18.

Del Piano, M., et al. (2012). The innovative potential of Lactobacillus rhamnosus LR06, Lactobacillus pentosus LPS01, Lactobacillus plantarum LP01, and Lactobacillus delbrueckii Subsp. delbrueckii LDD01 to restore the “gastric barrier effect” in patients chronically treated with PPI: a pilot study. Journal of clinical gastroenterology, 46, S18-S26

Islam, SU (2016). Clinical uses of probiotics. Medicine, 95(5).

Kajander, K., et al. (2005). A probiotic mixture alleviates symptoms in irritable bowel syndrome patients: a controlled 6‐month intervention. Alimentary pharmacology & therapeutics, 22(5), 387-394.

Francavilla, R., et al. (2010). A randomized controlled trial of Lactobacillus GG in children with functional abdominal pain. Pediatrics, 126(6), e1445-e1452.

Gawronska, A., et al. (2007). A randomized double-blind placebo-controlled trial of Lactobacillus GG for abdominal pain disorders in children. Alimentary pharmacology & therapeutics, 25(2), 177-184.

Odamaki, T., et al. (2012). Effect of the oral intake of yogurt containing Bifidobacterium longum BB536 on the cell numbers of enterotoxigenic Bacteroides fragilis in microbiota. Anaerobic, 18(1), 14-18.

Cardiovascular

Noad, R.L., et al. (2016). Beneficial effect of a polyphenol-rich diet on cardiovascular risk: a randomized control trial. Heart, 102(17), 1371-1379.

Nishimura, M., et al. (2015). Effects of the extract from roasted chicory (Cichorium intybus L.) root containing inulin-type fructans on blood glucose, lipid metabolism, and fecal properties. Journal of traditional and complementary medicine, 5(3), 161-167.

Guess, N.D., et al. (2015). A randomized controlled trial: the effect of inulin on weight management and ectopic fat in subjects with prediabetes. Nutrition & metabolism, 12(1), 36.

Andrade, S., & Borges, N. (2009). Effect of fermented milk containing Lactobacillus acidophilus and Bifidobacterium longum on plasma lipids of women with normal or moderately elevated cholesterol. Journal of dairy research, 76(4), 469-474.

psyche

Huang, R., et al. (2017). Efficacy of probiotics on anxiety: A meta-analysis of randomized controlled trials. Neuropsychiatry, 7(6), 862-871.

Kim, C.S., & Shin, D.M. (2019). Probiotic food consumption is associated with lower severity and prevalence of depression: A nationwide cross-sectional study. Nutrition, 63, 169-174.

Smith, A., et al. (2015). An investigation of the acute effects of oligofructose-enriched inulin on subjective wellbeing, mood and cognitive performance. Nutrients, 7(11), 8887-8896.

Srikantha, P., & Mohajeri, M.H. (2019). The Possible Role of the Microbiota-Gut-Brain Axis in Autism Spectrum Disorder. International journal of molecular sciences, 20(9), 2115.

Pärtty, A., et al. (2015). A possible link between early probiotic intervention and the risk of neuropsychiatric disorders later in childhood: a randomized trial. Pediatric research, 77(6), 823.

Cell

Amaretti, A., et al. (2013). Antioxidant properties of potentially probiotic bacteria: in vitro and in vivo activities. Applied microbiology and biotechnology, 97(2), 809-817.

Kerimi, A., & Williamson, G. (2016). At the interface of antioxidant signaling and cellular function: Key polyphenol effects. Molecular nutrition & food research, 60(8), 1770-1788.

Allergy

Drago, L., et al. (2015). Immunomodulatory effects of Lactobacillus salivarius LS01 and Bifidobacterium breve BR03, alone and in combination, on peripheral blood mononuclear cells of allergic asthmatics. Allergy, asthma & immunology research, 7(4), 409-413.

Manzotti, G., et al. (2014). Multi-strain Symbiotic Preparations as a Novel Adjuvant Approach to Allergic Rhinitis. Journal of Contemporary Immunology. 1. 67-80.

Enomoto, T., et al. (2014). Effects of bifidobacterial supplementation to pregnant women and infants in the prevention of allergy development in infants and on fecal microbiota. Allergology International, 63(4), 575-585.

Xiao, J. Z., et al. (2006). Probiotics in the treatment of Japanese cedar pollinosis: a double-blind placebo-controlled trial. Clinical & Experimental Allergy, 36(11), 1425-1435.

Xiao, JZ, et al. (2007).Clinical efficacy of probiotic Bifidobacterium longum for the treatment of symptoms of Japanese cedar pollen allergy in subjects evaluated in an environmental exposure unit. Allergology international, 56(1), 67-75.

Metabolism

Les, F., et al. (2018). Pomegranate polyphenols and urolithin A inhibit α-glucosidase, dipeptidyl peptidase-4, lipase, triglyceride accumulation and adipogenesis related genes in 3T3-L1 adipocyte-like cells. Journal of ethnopharmacology, 220, 67-74.

Ryu, D., et al. (2016). Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents. Nature medicine, 22(8), 879.

Thilakarathna, W. W., et al. (2018). Polyphenol-based prebiotics and synbiotics: potential for cancer chemoprevention. Current Opinion in Food Science, 20, 51-57.

Andreux, PA, et al. (2019). The mitophagy activator urolithin A is safe and induces a molecular signature of improved mitochondrial and cellular health in humans. Nature Metabolism, 1(6), 595.

Guess, N.D., et al. (2015). A randomized controlled trial: the effect of inulin on weight management and ectopic fat in subjects with prediabetes. Nutrition & metabolism, 12(1), 36

Minami, J.I., et al. (2015). Oral administration of Bifidobacterium breve B-3 modifies metabolic functions in adults with obese tendencies in a randomized controlled trial. Journal of nutritional science, 4.

Minami, J., et al. (2018). Effects of Bifidobacterium breve B-3 on body fat reductions in pre-obese adults: a randomized, double-blind, placebo-controlled trial. Bioscience of microbiota, food and health, 18-001.

Mogna, L., et al. (2014). Screening of different probiotic strains for their in vitro ability to metabolize oxalates: any prospective use in humans?. Journal of clinical gastroenterology, 48, S91-S95.

Immune system

Pregliasco, F., et al. (2008). A new chance of preventing winter diseases by the administration of synbiotic formulations. Journal of clinical gastroenterology, 42, S224-S233.

Klemenak, M., et al. (2015). Administration of Bifidobacterium breve Decreases the Production of TNF-α in Children with Celiac Disease. Digestive diseases and sciences, 60(11), 3386-3392.

Sugahara, H., et al. (2015). Probiotic Bifidobacterium longum alters gut luminal metabolism through modification of the gut microbial community. Scientific reports, 5, 13548.

Nicola, S., et al. (2010). Interaction between probiotics and human immune cells. Focus Diet Fibers Pre/Probiot, 21, 9-12.

Mogna, L., et al. (2018). Micronized Cells of the Probiotic Strain Bifidobacterium lactis BS01 Activate Monocyte Polarization: A New Approach. Journal of clinical gastroenterology, 52, S57-S61.

skin

Manzotti, G., et al. (2014). Probiotics as a Novel Adjuvant Approach to Atopic Dermatitis. Journal of Contemporary Immunology, 1. 57-66.

Lemoli, E., et al. (2012). Probiotics reduce gut microbial translocation and improve adult atopic dermatitis.Journal of clinical gastroenterology, 46, S33-S40.

Enomoto, T., et al. (2014). Effects of bifidobacterial supplementation to pregnant women and infants in the prevention of allergy development in infants and on fecal microbiota. Allergology International, 63(4), 575-585.

Mouth and Teeth

Del Piano, M., et al. (2014). Correlation between Specific Bacterial Groups in the Oral Cavity and the Severity of Halitosis: Any Possible Beneficial Role for Selected Lactobacilli. J Gastroint Dig Syst, 4(197

Nase, L., et al. (2001). Effect of long–term consumption of a probiotic bacterium, Lactobacillus rhamnosus GG, in milk on dental caries and caries risk in children. Caries research, 35(6), 412-420.

Urinary bladder

Vicariotto, F. (2014). Effectiveness of an association of a cranberry dry extract, D-mannose, and the two microorganisms Lactobacillus plantarum LP01 and Lactobacillus paracasei LPC09 in women affected by cystitis: a pilot study. Journal of clinical gastroenterology, 48, S96-S101.

Women

Holloway, L., et al. (2007). Effects of oligofructose-enriched inulin on intestinal absorption of calcium and magnesium and bone turnover markers in postmenopausal women. British Journal of Nutrition, 97(2), 365-372.

de Brito Alves, JL, et al. (2019). Gut microbiota and probiotic intervention as a promising therapeutic for pregnant women with cardiometabolic disorders: present and future directions. Pharmacological research, 104252.

Han, M. M., et al. (2019). Probiotics improve glucose and lipid metabolism in pregnant women: a meta-analysis. Annals of translational medicine, 7(5).

Reid, G. (2016). The development of probiotics for women's health. Canadian journal of microbiology, 63(4), 269-277.

Ocaña, VS, et al. (1999). Characterization of a bacteriocin-like substance produced by a vaginal Lactobacillus salivarius strain. Appl. Environ. Microbiol., 65(12), 5631-5635.

Ocaña, V., & Nader-Macías, M.E. (2001). Adhesion of Lactobacillus vaginal strains with probiotic properties to vaginal epithelial cells. Biocell: official journal of the Sociedades Latinoamericanas de Microscopia Electronica... et. al, 25(3), 265-273.

Ocaña, VS, & Nader-Macías, ME (2002). Vaginal lactobacilli: self-and co-aggregating ability. British journal of biomedical science, 59(4), 183-190.

Zárate, G., & Nader‐Macias, ME (2006). Influence of probiotic vaginal lactobacilli on in vitro adhesion of urogenital pathogens to vaginal epithelial cells. Letters in Applied Microbiology, 43(2), 174-180.

Ocaña, VS, et al. (1999). Surface characteristics of lactobacilli isolated from human vagina. The Journal of general and applied microbiology, 45(5), 203-212

Tomás, J., et al. (2002). Influence of pH, temperature and culture media on the growth and bacteriocin production by vaginal Lactobacillus salivarius CRL 1328. Journal of Applied Microbiology, 93(4), 714-724..